1-(2-吡啶偶氮)-2-萘酚號：85-85-8
英文名稱：PAN；1-(2-Pyridylazo)-2-naphthol
其他名稱：α-吡啶偶氮-β-萘酚；過氧硝酸己鹽酯；2-吡啶偶氮-2-萘酚；1-(2-聯(lián)氮吡啶)-2-萘酚
號：85-85-8
C15H11N3O=249.27
級別：AR
分光有效含量：≥90.0%
熔點：138～142℃(2℃)
銅絡(luò)合物摩爾吸收系數(shù)，ε/(L/cm·mol)：≥2.1×104
灼燒殘渣(以硫酸鹽計)：≤0.1%
乙醇溶解試驗：合格
性狀(以下信息僅供參考)：橙紅色無定形粉末。溶于甲醇、乙醇、苯、乙迷、方和熱稀堿液，不溶于水。溶液在pH12以上時，呈粉紅色，在弱酸中呈橙紅色，在濃硫酸中呈紫色。其金屬絡(luò)合物呈粉紅色或紅色。Z大吸收波長 462nm。有刺激性
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)絡(luò)合指示劑，滴定鉍、鎘、銅、鎵、銦、鑭系元素、鎳、鉛、釷、駝(III)、鈾、鋅。痕量金屬的沉淀富集。光度測定鈷、銅、三價鐵、鎵、汞、銦、銥、錳、鎳、鉛、鈀、銠、釕、銻、鈦、鈾、釩、鋅、鋯和鑭系元素
保存：RT，避光1-(2-吡啶偶氮)-2-萘酚號：85-85-8儲存條件：
避光、干燥陰涼處封閉貯存,嚴(yán)禁與有毒、有害物品混放、混運。本品為非危險 產(chǎn)品可按一般化學(xué)品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸：汽車運輸、EMS郵政快遞，申通快遞等， 款到上海3天內(nèi)發(fā)貨；
售后：如您對我們的產(chǎn)品服務(wù)及技術(shù)指標(biāo)有特殊要求，請及時通知我方。
存儲：應(yīng)貯存在干燥清潔避光的環(huán)境中，嚴(yán)禁與有毒物質(zhì)混放，以免污染（保質(zhì)期為兩年）。
1-(2-吡啶偶氮)-2-萘酚號：85-85-8主要優(yōu)級純、分級純和化學(xué)純3種：
（1）優(yōu)級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質(zhì)含量Z低，適合于重要精密的分析工作和科學(xué)研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優(yōu)級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學(xué)純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學(xué)校一般分析工作。使用藍色（深藍色）標(biāo)簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
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1
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011].
Function : Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Subunit : Homodimer. Interacts with DLG4; the interaction possibly being prevented by the association between and CAPON. Forms a ternary complex with CAPON and RASD1. Forms a ternary complex with CAPON and SYN1. Interacts with ZDHHC23. Interacts with NOSIP; which may impair its synaptic location (By similarity). Interacts with HTR4. Interacts with VAC14 (By similarity). Interacts with SLC6A4.
Subcellular Location : Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle 1-(2-吡啶偶氮)-2-萘酚號：85-85-8fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
Tissue Specificity : Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the plaets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Post-translational modifications : Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro) (By similarity).
Similarity : Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Contains 1 PDZ (DHR) domain.
Database links : UniProtKB/Swiss-Prot: P29475.2
一氧化氮合成酶-1催化生物體內(nèi)一氧化氮（NO）生成的酶。分神經(jīng)型一氧化氮合成的酶（nNOS or ）、誘導(dǎo)型一氧化氮合成的酶（iNOS or NOS2）、內(nèi)皮型一氧化氮合成的酶（eNOS or NOS3）。此抗體識別分子量為150kDa的神經(jīng)型一氧化氮合成的酶。
英文名稱 Anti-NR5A2/LRH1
中文名稱 成纖維細(xì)胞核受體Nr5a2抗體
