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矢車菊素葡萄糖苷號：7084-24-4   
英文名稱：Kuromanin chloride；Asterin；Chrysanthemin；Cyanidin 3-O-glucoside chloride   
其他名稱：2-(3,4-二羥基苯基)-3-(β-D-吡喃葡萄糖氧基)-5,7-二羥基-1-苯并化物；矢車菊苷；矢車菊素-3-O-葡萄糖苷；2-(3,4-二羥基苯基)-3-(β-D-吡喃葡萄糖氧基)-5,7-二羥基-1-苯并吡喃化物   
號：7084-24-4   
C21H21ClO11=484.84   
級別：BR   
純度：≥98%   
性狀(以下信息僅供參考)：粉末   
用途：本品僅供科研，不得用于其它用途   
保存：-20℃客戶根據(jù)矢車菊素葡萄糖苷號：7084-24-4性質(zhì)、化學式、分子式、結構式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況，本產(chǎn)品化學性質(zhì)穩(wěn)定，運輸條件不苛刻，一般儲存在陰涼，干燥，通風良好的地方，遠離不相容的物質(zhì)。保持容器密閉。
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 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Shootin1 is a 631 amino acid protein that belongs to the shootin family. The shootin1 protein contains three coiled-coil domains, a proline-rich region and interacts with RUFY3. Shootin1 is involved in the generation of internal asymmetric signals required for neuronal polarization. The shootin1 protein acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. By accumulating asymmetrically in a single neurite before polarization, shootin1 leads to axon induction for polarization, additionally the absence of shootin1 from the nascent axon's siblings by competition prevents the formation of surplus axons. Existing as seven alternatively spliced isoforms, the shootin1 gene is conserved in chimpanzee, dog, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q25.3.
Function : Involved in the generation of internal asymmetric signals required for neuronal polarization. Acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. Accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axon's siblings by competition preventing the formation of surplus 矢車菊素葡萄糖苷號：7084-24-4axons.
Subunit : Interacts with RUFY3
Subcellular Location : Cell projection
Similarity : Belongs to the shootin family.
Database links : UniProtKB/Swiss-Prot: A0MZ66.4
英文名稱  Anti-SCDO3/Lunatic Fringe
中文名稱  信號轉導分子SCDO3抗體
別    名  3-N-acetylglucosaminyltransferase lunatic fringe; Beta-1; Beta-13-N-acetylglucosaminyltransferase lunatic fringe; lfng; LFNG_HUMAN; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型  一抗   
研究領域  細胞生物 發(fā)育生物學 神經(jīng)生物學 信號轉導 
蛋白分子量  predicted molecular weight: 42kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human SCDO3/Lunatic Fringe
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Three mammalian fringe family members, namely Manic Fringe, Radical Fringe and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Lunatic Fringe, also known as LFNG or SCDO3, is a 379 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus. Functioning as a glycosyltransferase, Lunatic Fringe acts a critical mediator of somite patterning and segmentation and plays a fundamental role in initiating the elongation of O-linked fucose residues that are attached to Notch molecules. Defects in the gene encoding Lunatic Fringe are the cause of autosomal recessive spondylocostal dysostosis 3 (SCDO3), a disorder that arises during embryonic development and is characterized by rib anomalies and multiple vertebrate segmentation. Three isoforms of Lunatic Fringe are expressed due to alternative splicing events.
Function : Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning.
Subcellular Location : Golgi apparatus membrane; Single-pass type II membrane protein
Post-translational modifications : A soluble form may be derived from the membrane form by proteolytic processing.
DISEASE : Defects in LFNG are the cause of spondylocostal dysostosis type 3 (SCDO3) [MIM:609813]. An autosomal recessive condition of variable severity associated with vertebral and rib segmentation defects. The main skeletal malformations include fusion of vertebrae, hemivertebrae, fusion of certain ribs, and other rib malformations. Deformity of the chest and spine (severe scoliosis, kyphoscoliosis and lordosis) is a natural consequence of the malformation and leads to a dwarf-like appearance. As the thorax is small, infants frequently have respiratory insufficiency and repeated respiratory infections resulting in life-threatening complications in the first year of life.
Similarity : Belongs to the glycosyltransferase 31 family.
Database links : UniProtKB/Swiss-Prot: Q8NES3.2
英文名稱  Anti-L-Selectin/CD62L
中文名稱  L選擇素抗體
別    名  A.11; AI528707; CD62 antigen ligand; CD62 antigen-like family member L; gp90 MEL; hLHRc; IgA nephropathy, susceptibility to, included; L Selectin; LAM1; LECAM1; LEU8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; Ly-22; Ly-m22; Lyam-1; LYAM1; Lymph node homing receptor; Lymphocyte adhesion molecule 1; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; PLNHR; Selectin L; Selectin, lymphocyte; SELL; TQ1; LYAM1_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.1ml/100μg  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human
產(chǎn)品類型  一抗   
研究領域  心血管 細胞生物 免疫學 干細胞 淋巴細胞 t-淋巴細胞 b-淋巴細胞 
蛋白分子量  predicted molecular weight: 37kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human L-Selectin (112-154aa)
亞    型  IgG