背景介紹：This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.

Function:
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Activity is regulated by MICU1 and MICU2 that stimulate and inhibit MCU activity, respectively. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes.

別名：MCU_HUMAN; C10orf42; Ccdc109a; Coiled-coil domain-containing protein 109A; Mitochondrial Calcium Uniporter. 

線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體,MCU抗體簡單介紹：

產(chǎn)品編號：BYK-18739R

英文名稱：Anti-MCU
中文名稱：線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

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性    狀 Lyophilized or Liquid
濃    度 1mg/ml

線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體,MCU抗體產(chǎn)品信息：

免疫熒光單染（間接法）
1.石蠟切片正常脫蠟至水，PBS洗5分鐘，2次
2.抗原修復(fù)，0.01M枸櫞酸修復(fù)液，沸水浴熱修復(fù)15分鐘
3.正常山羊血清封閉20分鐘，37℃
4.一抗孵育，4℃過夜。
5.PBS洗5分鐘，3次
6.熒光標記二抗孵育，37℃，90分鐘
7.PBS洗5分鐘，3次
8.DAPI復(fù)染，PBS洗5分鐘，3次
9.防淬滅熒光封片劑封片
10.鏡檢

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