![Ryanodine, [9,21-3H(N)]-, 250µCi (9.25MBq)](https://img80.ybzhan.cn/5eceadd4559dcfd26d62455fac166a8617e262c77a9b7f5ba2fde8676dc652dda92f5308d17617a7_800_800_5.jpg)
Ryanodine is a plant alkaloid and natural ligａnd for the ryanodinen receptor (RyR), a class of calcium channels (Ca2+ channels).
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New Englａnd Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET950:
- Araki, T., Kato, H., Shuto, K., Oshima, Y. and Itoyama, Y. (1998), Postischemic changes of [3H]nimodipine and [3H]ryanodine binding in the gerbil striatum and hippocampus. European Journal of Neurology, 5: 195–201.
規(guī)格
| 濃度 | <1.0> |
|---|---|
| 檢測(cè)方法 | Radiometric |
| 標(biāo)簽位置 | Nominally Labeled |
| 分子量 | 493.5 |
| 產(chǎn)品品牌名稱 | NEN Radiochemicals |
| 放射性同位素 | H-3 |
| 放射性核素 | 3H |
| 受體類型 | Calcium |
| 運(yùn)輸條件 | 干冰 |
| 特殊訂購(gòu)信息 | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| 治療領(lǐng)域 | CNS & Neurologic, Musculoskeletal |
| 產(chǎn)品尺寸 | 250 µCi |
