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Anti-Desmin/DES抗體價(jià)格

時(shí)間:2014-3-26閱讀:145
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Rabbit  Anti-Desmin/DES抗體價(jià)格

FROM:ABCAM
Catalog Number : BYK-1026R       
Quantity size :   0.1ml  (dilute with pH 7.4    0.01 M PBS or antibody diluent )

Anti-Desmin/DES抗體價(jià)格Background:  filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin antibodies are useful in identification of tumours of myogenic origin.

Specificity :   

  • Anti-Desmin/DES is a rabbit polyclonal antibody unconjugated                
  • specific for Desmin/DES of human, rat,mo          
  • use for western blotting,elisa,immunoprecipitation and immunohistochemistry
  • Protein G affinity chromatography purification, purity :>95%
  • Isotype:  IgG
  • mol wt:  52kDa

Anti-Desmin/DES抗體價(jià)格Application :  

  • Western blotting 1:100-500                
  • Immunohistochemistry 1:100-500                  
  • ELISA 1:500-1000                  
  • Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20 for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4

Anti-Desmin/DES抗體價(jià)格Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.

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